前沿速览030期| CAR-T治B淋 前沿览新知

01

CAR-T细胞与T细胞疗法在癌症治疗中的应用:转化科学综述
CAR T Cells and T-Cell Therapies for Cancer: A Translational Science Review
第一作者:Brudno JN
JAMA(IF=63.1). 2024 Nov 4.
全文网址:https://jamanetwork.com/journals/jama/article-abstract/2825799
02

运用T细胞重定向策略构建滤泡性淋巴瘤的未来管理
Building the Future Management of Follicular Lymphoma with T-Cell-Redirecting Strategies
第一作者:Iacoboni G
Blood(IF=21.0). 2024 Nov 14:blood.2024025699.
全文网址:https://ashpublications.org/blood/article-abstract/doi/10.1182/blood.2024025699/525990/Building-the-Future-Management-of-Follicular?redirectedFrom=fulltext
03

加速与优化CAR-T细胞制备,为患者提供更优质的治疗产品
Accelerating and optimising CAR T-cell manufacture to deliver better patient products
第一作者:Agliardi G
Lancet Haematol(IF=15.4). 2024 Nov 4:S2352-3026(24)00273-4.
全文网址:https://linkinghub.elsevier.com/retrieve/pii/S2352-3026(24)00273-4
04

CAR-T是药物还是疗法?复发/难治性弥漫性大B细胞淋巴瘤患者接受CAR-T细胞治疗的真实世界研究:意向性治疗与符合方案分析
Is CAR T a drug or a therapeutic pathway? Intention to treat versus per protocol analysis of real world studies of CAR-T cell therapy in relapsed refractory diffuse large B cell lymphoma
第一作者:Di Staso R
Blood Cancer J(IF=12.9). 2024 Nov 7;14(1):197.
全文网址:https://www.nature.com/articles/s41408-024-01183-8
05

CAR-T细胞治疗相关血液毒性的新见解:临床表现、作用机制与有效的管理策略
New insights into CAR T-cell hematological toxicities: manifestations, mechanisms, and effective management strategies
第一作者:Yang Y
Exp Hematol Oncol(IF=9.4). 2024 Nov 9;13(1):110.
全文网址:https://ehoonline.biomedcentral.com/articles/10.1186/s40164-024-00573-9
06

自体CD19 CAR-T细胞治疗复发/难治性弥漫大B细胞淋巴瘤的疗效评估模型及疗效风险因素
An assessment model for the efficacy of autologous CD19 chimeric antigen receptor T-cell therapy and relapse or refractory diffuse large B-cell lymphoma risk
第一作者:Xue B
Chin Med J (Engl)(IF=7.5). 2024 Nov 6.
全文网址:https://journals.lww.com/cmj/fulltext/9900/an_assessment_model_for_the_efficacy_of_autologous.1310.aspx
07

真实世界中商业化axicabtagene ciloleucel和lisocabtagene maraleucel治疗大B细胞淋巴瘤的结局比较
A real-world comparison of commercial use axicabtagene ciloleucel and lisocabtagene maraleucel in large B-cell lymphoma
第一作者:Looka A
Blood Adv(IF=4.6). 2024 Nov 15:bloodadvances.2024012992.
全文网址:https://link.springer.com/article/10.1007/s00262-024-03855-7
08

38例复发/难治性的原发性或继发性中枢神经系统淋巴瘤患者在自体造血干细胞移植后接受CAR-T细胞治疗的临床结局
Clinical outcomes of chimeric antigen receptor T-cell therapy following autologous hematopoietic stem cell transplantation in 38 patients with refractory/relapsed primary or secondary central nervous system lymphoma
第一作者:Wu J
Cancer Immunol Immunother(IF=4.6). 2024 Nov 11;74(1):17.
全文网址:https://link.springer.com/article/10.1007/s00262-024-03855-7
09

非霍奇金淋巴瘤患者在CAR-T细胞治疗失败后的策略选择
Strategies following failure of CAR-T-cell therapy in non-Hodgkin lymphoma
第一作者:Zhang X
Bone Marrow Transplant(IF=4.5). 2024 Nov 12.
全文网址:https://www.nature.com/articles/s41409-024-02463-4
10

在Axicabtagene ciloleucel治疗大B细胞淋巴瘤患者中,预防性使用IL-6受体抑制剂的风险警示
Cautionary Tale of Unopposed Prophylactic IL6 Receptor Blockade in Axicabtagene ciloleucel for Large B-Cell Lymphoma
第一作者:Valtis YK
Transplant Cell Ther(IF=3.6). 2024 Nov;30(11):1042-1044.
全文网址:https://linkinghub.elsevier.com/retrieve/pii/S2666-6367(24)00699-7
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审批编号:NP-NHL-2024.11-18 valid until 2026.11
供稿与审核:临床开发与医学部